Dr. Swetlana Gautam

Assistant Professor
Pharmacology


Professional Biography

Swetlana Gautam is is an expert in the area of Pharmacology and preclinical Pharmacology. She has taught these subjects previously at BS Anangpuria Institute of Pharmacy, Faridabad.

Before taking up the current assignment in 2019, Swetlana Gautam worked at BS Anangpuria Institute of Pharmacy, Faridabad.

She accomplished her Post graduation in Pharmacology in 2013, and was awarded with Ph.D. in Pharmaceutical Sciences, Baba Saheb Bhimrao Ambedkar University, Lucknow in 2018.

Publications (from 2015)

Scholarly Journal
‘DuCLOX-2/5 inhibition attenuates inflammatory response and induces mitochondrial apoptosis for mammary gland chemoprevention’, Frontiers in Pharmacology, 9, pp. 314. (Gautam, S., Rawat, A.K., Sammi, S.R., Roy, S., Singh, M., Devi, U., Yadav, R.K., Singh, L., Rawat, J.K., Ansari, M.N., Saeedan, A.S., Kumar, D., Pandey, R., and Kaithwas, G. 2018).

‘Effects of Phenidone (DuCLOX-2/5 inhibitor) against N-Methyl-N-Nitrosourea induced mammary gland carcinoma in Albino rats’,Toxicology and Applied Pharmacology, 351, pp. 57-63. (Gautam, S., Rani, S., Aldossary, S.A.,Saeedan, A.S., Ansari, M.N., andKaithwas, G. 2018).

‘Rifaximin, a Pregnane X Receptor (PXR) Activator regulates apoptosis in Murine Model of Breast Cancer’ RSC Advances’, 8, pp. 3512-3521. (Gautam, S.,Singh, P., Singh, M., Roy, S., Rawat, J.K, Yadav, R.K., Devi, U., Gupta, P.S., Saraf, S.A., and Kaithwas, G., 2018).

‘Effects of minocycline and doxycycline against terbutaline induced early postnatal autistic changes in albino rats’, Physiology & Behavior, 183, pp. 49-56. (Rani, V., Gautam, S., Rawat, J.K., Singh, M., Devi, U., Yadav, R.K., Roy, S., and Kaithwas, G. 2018).

‘GLA supplementation regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DMBA induced mammary gland carcinoma’, The international Journal of Biochemistry & Cell Biology, 96, pp. 51-62 (Roy, S., Singh, M., Rawat, A.K., Devi, U., Gautam, S., Yadav, R.K., Rawat, J.K., Ansari, M.N., Saeedan, A.S., Kumar, D., Kaithwas, G. 2018).

‘Galantamine attenuates N, N-dimethyl hydrazine induced neoplastic colon damage by inhibiting acetylcholinesterase and bimodal regulation of nicotinic cholinergic neurotransmission’, European Journal of Pharmacology, 818, pp. 174-83. (Sammi, S.R.,Rawat, J.K.,Raghav, N., Kumar, A., Roy, S., Singh, M., Gautam, S., Yadav, R.K., Devi, U., Pandey, R., and Kaithwas, G. 2018).

‘Alpha-linolenic acid arbitrates mitochondrial apoptosis, curbs the hypoxic microenvironment and de novo fatty acid synthesis to impart anticancer effects’ Oncotarget, 8(41), pp. 70049. (Roy, S., Rawat, A.K., Sammi, S.R., Devi, U.,Singh, M., Gautam, S., Yadav, R.K.,Rawat, J.K.,Singh, L., Ansari, M.N., Saeedan, A.S., Pandey, R.,Kumar, D., and Kaithwas, G.,2017).

‘DuCLOX-2/5 inhibition: a promising target for cancer chemoprevention’ Breast Cancer. pp. 1-11. (Gautam, S., Roy, S., Ansari, M.N., Saeedan, A.S., Saraf, S.A., and Kaithwas, G. 2016).

‘Experimental models for autism spectrum disorder follow-up for the validity’ Review Journal of Autism and Developmental Disorders, 3(4), pp. 358-376. (Devi, U., Kumar, V., Gupta, P.S., Dubey, S., Singh, M., Gautam, S., Rawat, J.K., Roy, S., Yadav, R.K., Ansari, M.N.,Saeedan, S.A., andKaithwas, G. 2016).

‘Palonosetron attenuates 1, 2-dimethyl hydrazine induced preneoplastic colon damage through downregulatingacetylcholinesterase expression and up-regulating synaptic acetylcholine concentration’ RSC Advances, 6(46), pp. 40527-40538. (Mishra, R.K.,Sammi, S.R., Rawat, J.K., Roy, S., Singh, M., Gautam, S.,Yadav, R.K., Devi, U., Ansari, M.N., Saeedan, A.S., Saraf,S.A., Pandey, R., and Kaithwas, G. 2016).

‘Redefining the role of peripheral LPS as a neuroinflammatory agent and evaluating the role of hydrogen sulphide through metformin intervention’Inflammopharmacology24(5), pp. 253-264. (Tiwari, V., Singh, M., Rawat, J.K., Devi, U., Yadav, R.K., Roy, S., Gautam, S.,Saraf, S.A., Kumar, V., Ansari, M.N.,Saeedan, A.S., and Kaithwas, G. 2016).

‘Comparative efficacy of alpha-linolenic acid and gamma-linolenic acid to attenuate valproic acid-induced autism-like features’, Journal of Physiology and Biochemistry, pp. 1-12. (Yadav, S., Tiwari, V., Singh, M., Yadav, R.K., Roy, S., Devi, U., Gautam, S., Rawat, J.K., Ansari, M.N., Saeedan, A.S., Prakash, A., Saraf, S.A., and Kaithwas, G. 2016).

‘α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats’, Inflammopharmacology, 24(5), pp. 277-286. (Rani, A., Roy, S., Singh, M., Devi, U., Yadav, R.K., Gautam, S.,Rawat, J.K.,Ansar, M.N., Saeedan, A.S.,Prakash, A., and Kaithwas, G. 2016).

‘Effect of β-sitosterol against methyl nitrosourea-induced mammary gland carcinoma in albino rats’, BMCComplementary and Alternative Medicine, 16(1), pp. 260. (Manral, C., Roy, S., Singh, M., Gautam, S., Yadav, R.K., Rawat, J.K., Devi, U., Ansari, M.N., Saeedan, A.S., and  Kaithwas, G. 2016).

‘Rutin attenuates intestinal toxicity induced by Methotrexate linked with anti-oxidative and anti-inflammatory effects’, BMC complementary and alternative medicine, 16(1), pp. 99. (Gautam, R., Singh, M., Gautam, S., Rawat, J.K., Saraf, S.A., and Kaithwas, G. 2016).

‘Correction: Preclinical appraisal of terbutaline analogues in precipitation of autism spectrum disorder’ RSC Advances, 5(127), pp. 104972. (Sharma, N., Gautam, S., Devi, U., Singh, M., Rawat, J.K., Sethi, N., Saraf, S.A., and Kaithwas, G. 2016).

‘Preclinical appraisal of terbutaline analogues in precipitation of autism spectrum disorder’, RSC Advances, 5(49), pp. 39003-39011. (Sharma, N., Gautam, S., Devi, U., Singh, M., Rawat, J.K., Sethi, N., Saraf, S.A., and Kaithwas, G. 2015).

‘Effect of palonosetron (5HT-3 antagonist) and pantoprazole (PPI) against surgical esophagitis induced by forestomach and pylorus ligation in albino rats’, Human and Experimental Toxicology, pp. 41-50. (Kumar, A., Gautam, S., Rawat, J.K., Singh, M., Saraf, S.A., andKaithwas, G. 2015).

‘Efficacy of variable dosage of aspirin in combating methotrexate-induced intestinal toxicity’, RSC Advances, 5, pp. 9354-9360. (Gupta, S.K., Gautam, S., Rawat, J.K., Singh, M., Saraf, S.A., and Kaithwas, G. 2015).

‘Effect of lycopene against gastroesophageal reflux disease in experimental animals’, BMC complementary and alternative medicine, 15(1), pp. 110. (Giri, A.K.,Rawat, J.K., Singh, M., Gautam, S.,and Kaithwas, G. 2015).

Research Monographs, Books and Book Chapters

‘Pollutants in tannery wastewater, their pharmacological effects and bioremediation approaches for human health protection and environmental safety’ In book: Environmental Pollutants and their Bioremediation Approaches (pp. 362-382): CRC Press, Taylor & Francis Group, USA. (Gautam, S., Kaithwas, G.,Bharagava, R.N., Saxena, G., 2017).

Current Research

Understand the mechanistic link between the lipids and proteins interactions intumorigenesis and its prevention. She is actively engaged in Biochemical Pharmacology, Carcinogenesis, Apoptosis and differentiation, and developing therapeutic alternatives for cancers associated with lipoidal tissues.